Fisetin from fruits and vegetables protects the aging brain and helps fight cancerNote from Carolyn:
Our fruits provide more than just a sweet taste to the meal. Note that this
article talks about natural fruts. Canned and processed fruits don't count!
Article continues ...
is a unique flavonoid compound found naturally in many fruits and vegetables
including strawberries, blueberries and the skin of cucumbers. A wealth of
scientific research now explains how a diet packed with raw fruits and
vegetables can help prevent amyloid plaque formation in the aging brain and can
promote the early destruction of cancer cells by triggering the body's innate
immune response. Researchers reporting in the journal Neuroscience
Letters found that fisetin is neuro-protective and helps to maintain normal
memory processes while inhibiting plaque formation around synapses. The
International Journal of Oncology has published the work of Chinese
scientists documenting how fisetin promotes the natural death of potentially
malignant breast cancer cells. Fisetin is rapidly emerging as a powerful tool in
the arsenal against a number of diseases associated with premature
Fruits and vegetables in their natural state are typically packed
with polyphenols; these polyphenols are structurally bioactive and target
specific areas of the body or help to lower oxidative stress and inflammation
that is behind many disease processes. The brain is particularly sensitive to
stress from a high rate of metabolism necessary to oxygenate and fuel the
sensitive neurons that control memory and cognition.
Fisetin Helps Prevent Inflammation in the Brain to Boost Memory and
CognitionResearchers have found that fisetin operates in a very specific
pathway to boost nerve cell glutathione levels and to reduce one of the most
damaging free radicals, peroxynitrite. Scientists have determined that the
natural compound protects nerve cells from damage during stroke, while at the
same time maintaining vital energy production in the brain. Fisetin also
prevents excess activation of specialized glial cells in the brain that helps
deter inflammatory nerve damage, excitotoxicity, and declining neurological
health. And fisetin reduces amyloid beta fiber accumulation to improve memory
and thwart cognitive decline.
In a separate body of research, scientists
examined the effect of fisetin from dietary and supplemental sources on breast
cancer programmed cell death. Cancer cells normally are detected and destroyed
by an alert immune system response. Inflammatory messengers such as TNFa (tumor
necrosis factor alpha) allow cancer cells to become cloaked and invisible to our
immune system, which prevents cancer cell death through the process known as
apoptosis. Fisetin negates the damaging effect of TNFa, reducing systemic
inflammation and enabling the normal immune response.
health-conscious individuals may not be immediately familiar with fisetin,
although they already consume therapeutic quantities from their healthy dietary
Nutrition experts recommend including fruits such as strawberries
and mangoes as a source of dietary fisetin or supplementing with 50 mg per day
to boost memory and high-level brain function and to promote natural cancer cell
Sources for this article include:
John Phillip - Natural News
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